Beta-2 Microglobulin (Renal Failure & Tumor Marker) MBS438760 from MyBioSource.com

Product Specs
ItemBeta-2 Microglobulin (Renal Failure & Tumor Marker)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS438760
Quantity0.1 mg
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman, Non-Human Primates
TargetBeta-2 Microglobulin
IsotypeIgG2b kappa
Molecular WeightAntigen: 12kDa
CloneB2M/961
HostMouse
ImmunogenRecognizes a protein of 12kDa, identified as beta -2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha 1, alpha 2, alpha 3) and a non-covalent associating light chain, known as beta -2-Microglobulin. beta -2-Microglobulin associates with the alpha 3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha 1 and alpha 2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta -2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes
NCBI Full Gene Namebeta-2-microglobulin
ClonalityMonoclonal